Rapid advances in high throughput genomic technologies and next generation sequencing are making medical genomic research more readily accessible and affordable, including the sequencing of patient and control whole genomes and exomes in order to elucidate genetic factors underlying disease. Over the next five years, the Human Heredity and Health in Africa (H3Africa) Initiative, funded by the Wellcome Trust (United Kingdom) and the National Institutes of Health (United States of America), will contribute greatly towards sequencing of numerous African samples for (...) biomedical research. (shrink)

This chapter contains sections titled: I II III IV V VI VII VIII IX X.

Os Cursos da Sorbonne de Merleau-Ponty tratam da psicologia e pedagogia da criança. Dentre outros tópicos, interessa-nos aqui a perspectiva fenomenológica merleau-pontiana acerca da relação entre intencionalidade e aquisição de linguagem. Ancorado no pensamento de Max Scheler e, sobretudo, Ferdinand de Saussure, Merleau-Ponty apresenta uma noção de linguagem que visa examinar as posições intelectualista e empirista de modo a superar a privacidade do cogito tácito e os limites do alter ego de Husserl, indicando assim uma origem intercorporal do fenômeno linguístico (...) em que outrem opera o descentramento do eu pela fala. (shrink)

Recent observations of ultra high energy cosmic rays and gamma rays suggest that there are small violations of Lorentz symmetry. If there were no such violations, then the GZK cut off would hold and cosmic rays with energy ∼1020 eV or higher would not be reaching the earth. However some such events seem to have been observed. This has lead to phenomenological models in which there is a small violation of the Lorentz symmetry or the velocity of light. However recent (...) approaches which no longer consider a differentiable spacetime manifold already predict such violations. Similarly there are other theoretical reasons which also point to this. We briefly discuss some of these approaches and observe that Lorentz Symmetry violations can be tested by data from NASA’s GLAST satellite due for launch. (shrink)

This article argues that in Pindar's epinicians first-person statements may occasionally be made in the persona of the chorus and the athletic victor. The speaking persona behind Pindar's first-person statements varies quite widely: from generic, rhetorical poses—a laudator, an aoidos in the rhapsodic tradition (the “bardic first person”), an Everyman (the “first person indefinite”)—to strongly individualized figures: the Theban poet Pindar, the chorus, the victor. The arguable changes in the speaker's persona are not explicitly signalled in the text. This can (...) lead to significant ambiguities concerning the identity of the speaker (“blurred quotation,” “indeterminate speech boundaries”). The lack of a concern always to distinguish clearly the primary from the secondary narrators relates to a desire to confuse diegetic and mimetic forms; the practice of the fifth-century choral lyric poets in this regard is compared to that of other ancient Greek writers. The main challenge is to indicate how it is possible, in theory and in practice, for the athletic victor to be identified as the speaker when this is not explicitly signalled in the text; and, if this is possible, to suggest how it is possible for an audience to recognize when the speaking persona subsequently reverts to laudator or poet. An attempt is made to consider whether any formal, structural, or thematic tendencies can be observed in those passages in choral lyric where the chorus or the victor are tacitly introduced as speaking personae: such effects, it is argued, occur especially when links of ritual or genealogy enable the ode to “zoom” from the mythical past to the present occasion of the performance. The main passages discussed in the article are Pind. P.8.56–60, P.9.89–92, N.7.85, Pae. 2.73–79, and Bacch. 3.84–85. But the phenomena discussed are related broadly to other phenomena in Greek literature, in Latin poetry, and, especially, in Cicero's forensic oratory. (shrink)

On December 7, 1994, the U.S. District Court of the Northern District of Illinois ruled that ERISA preempts a participant in an ERISA plan from suing the plan's administrator under a state common law theory of respondeat superior ) : at 208). On September 12, 1995, the Seventh Circuit of the U.S. Court of Appeals reversed this decision and ordered that the case be tried in state court ). The court held that the case had been improperly removed to federal (...) court. The court of appeals stated that the federal court did not have jurisdiction because the plaintiff's claim did not fall within ERISA's provisions.In this case, plaintiff David Rice brought a medical malpractice suit against two doctors who provided treatment to him in accordance with his ERISA insurance plan. (shrink)